A debilitating autoimmune disease.

‘During the last decade our research applications have been fundamental to numerous discoveries in lupus and have helped countless medical professionals develop a greater understanding of the disease that will ultimately result in better patient care.’ Under the organization’s Focus on Identification in Lupus grant program, as soon as approved through the organization’s rigorous, multi-level peer review, investigators leverage a two-year award to eliminate the barriers to brand-new treatments and a feasible cure. Related StoriesGenetic reduced amount of AMPK enzyme can prevent or delay hearing lossResearchers recognize tumor suppressor genes that travel subset of melanomasMoffitt Cancer Center study finds link between common gene mutations and tumor immune surveillanceIncluding in this round of awards are innovative research to: evaluate the role that DNA has in activating specific proteins which are thought to aggravate lupus; know how interferon utilizes particular proteins to promote blood vessel and kidney damage; assess lupus susceptibility because of rare genetic variants; determine the interaction that takes place between B-cells and T – which may encourage inflammation; characterize genetic alterations in certain immune cells and their contribution to the disease; assess disease progression and the relationship to particular alterations in dendritic cells; investigate the effect of activating proteins that reduce the discharge of interferon and, as a result, the severity and symptoms of lupus; analyze and understand particular gene activity through the three stages of lupus nephritis; characterization of the remission-inducing suppressor cells; and, to understand how the IRF5 gene could be modified or inhibited to change the span of the disease.Accelrys releases Discovery Studio software program for biotherapeutics research Accelrys, Inc. The release incorporates the initial available software for predicting protein-protein aggregation to advance biotherapeutics research commercially. As a key application in the Modeling and Simulation pillar of the Accelrys Business R&D Architecture, Discovery Studio extends comprehensive modeling and simulation capabilities and knowledge from experts to the enterprise, combining collaborative research from Accelrys and leading academic and research organizations on a unified system.