Exacerbations were significantly associated with worsening lung function , greater impairment in health status , a past background of gastroesophageal reflux, and an elevated white-cell count. Balance of the Frequent-Exacerbation Phenotype To assess the balance of the frequent-exacerbation phenotype over time, we first assessed how well individuals’ recall of treated exacerbations in the year before research entry predicted the number of exacerbations in calendar year 1, calculating positive predictive values and negative predictive values.Terms of the deal were not disclosed. Working with partner labs in India, China and Australia, ACM Global has effectively provided central laboratory providers in Asia Pacific for more than 15 years. By obtaining Phoenix PCS, ACM Global benefits an established, fully-operational laboratory in the center of Singapore that provides its clients a local team with extensive scientific trials experience and understanding of regional regulatory requirements, country specific logistics, and knowledge of customs and regional languages. Additionally, ACM Global will acquire Phoenix PCS' brand new laboratory service in Shanghai, China. With two laboratory places in Asia Pacific, ACM Global is able to provide local support of medical trials throughout the region with increased speed and efficiency.