Based on the best available details, the duration of storage of red cell units does not appear to affect clinical outcomes, O’Neill added.. ‘Older’ Blood Poses No Harm to Heart Surgery Patients: Research: – TUESDAY, Oct. 20, 2015 – – ‘Older’ bloodstream is simply as safe for center individuals as transfusions of fresher blood, a fresh study shows. Researchers in Sweden found that heart surgery individuals given bloodstream stored for a lot more than six weeks faced no greater damage than those who got bloodstream donated within the prior two weeks. Prior studies experienced reported that sufferers who undergo heart medical procedures and are transfused with blood vessels stored for more than two weeks have even worse survival and even more complications than individuals who are transfused with fresh new blood, said study author Dr.And European countries that suffer acute, life-threatening porphyria attacks every full year; there are 500 individuals afflicted with recurrent debilitating attacks approximately, often occurring once per month. Treatment plans for AIP patients suffering from an attack are limited, you need to include the use of heme preparations that show limited efficacy and so are associated with a number of complications. Currently, there are no drugs available to prevent episodes from occurring. Alnylam's approach is to knock down ALAS-1, an enzyme upstream of porphobilinogen deaminase , the defective gene in AIP.