The analysis showed that after 38 weeks of Soliris treatment.

Alexion Pharmaceuticals announces positive data from AEGIS research of Soliris Alexion Pharmaceuticals, Inc. The analysis showed that after 38 weeks of Soliris treatment, all patients with chronic kidney disease , a clinical consequence of chronic hemolysis, either stabilized or improved . Other studies show that kidney disease accounts for 18 % of deaths among Japanese sufferers with PNH. In the studied patients, Soliris therapy was associated with a sustained decrease also in hemolysis, which led to an additional improvement in levels of fatigue, in addition to a taken care of improvement in anemia and a decrease in transfusion requirements. In this extension study, medical improvements in kidney function with eculizumab therapy were obvious in sufferers with early particularly stage kidney disease, which underscores the need for early intervention with eculizumab, said Yuzuru Kanakura, M.D., Ph.D., Professor of Hematology and Oncology at Osaka University Medical center in Suita, Japan, and lead writer of the study.

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